产品货号:
Z23780
中文名称:
PLEKHM3抗体
英文名称:
Anti-PLEKHM3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PLEKHM3 Antibody |
指标别名 | DAPR,PLEKHM1L,Pleckstrin homology domain-containing family M member 3,PH domain-containing family M member 3 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | PLEKHM3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | PLEKHM3 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human PLEKHM3.The immunogen is located within the last 50 amino acids of PLEKHM3. |
计算分子量 | 87kDa |
成分 | PLEKHM3 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | PLEKHM3 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | PLEKHM3,also known as DAPR,is a member of the M family of Pleckstrin homology domain-containing proteins.PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2.In C2C12 myoblast cells,PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes.Following the initiation of differentiation,PLEKHM3 was also found in membrane fractions.Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation,suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis. |
Uniprot ID | Q6ZWE6 |
基因名全称 | Pleckstrin homology domain containing,family M,member 3 |
蛋白名全称 | Pleckstrin homology domain containing,family M,member 3 |
推荐稀释比 | PLEKHM3 antibody can be used for detection of PLEKHM3 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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